Examining metabolic therapy for brain cancer

Metabolic oncology is a relatively new area of cancer research and has the potential to offer new insights into cancer cells’ molecular flexibility, new biomarkers and even targeted therapies. “Metabolism” in this context refers to the metabolic activity inside cancer cells, not the rate at which the body processes energy from food.
Cancer cells are hungry. To feed their rapid growth and division, their metabolism changes. Moreover, they use sugar (glucose) in a different way to normal cells.

The animation below, created by Nature Reviews Drug Discovery, explores the key aspects of the altered metabolism in cancer cells and explains how these can be exploited for the development of new anticancer strategies.

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‘Fat but fit’ a gross exaggeration, says new study

Medical | UIG | Getty Images Man measures waist with measuring tape

Medical research has previously suggested that obesity can have little impact on a person’s chances of contracting various harmful diseases if they are otherwise medically healthy. However, the latest research, which tracked obese but “metabolically healthy” people, found that they continued to be at higher risk of developing diabetes and heart-related diseases later in life.

Dr Rishi Caleyachetty, who led the research, said the new research indicates that health professionals need to change their approach to obesity cases.”This is the largest prospective study of the association between metabolically health obesity and cardiovascular disease events.

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Crash Test Dummies 100 lbs Heavier

Crash test dummies, otherwise known as full-scale anthropomorphic test devices, which is a bit harder to say, like these ones at Ford Motor Company’s Dearborn Development Center are supposed to represent “typical” Americans. (AP Photo/Duane Burleson)

In order to make them simulate realistic human beings, crash test dummies will be heavier.  A sad reflection on the obesity epidemic!

For years, standard dummies have been 5-foot-9 and 170 pounds. But as CBS News reports, Humanetics, the leading maker of crash test dummies, will be making a heavier (by 100 pounds) and taller (by a few inches) dummy to better represent Americans.

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Scrambler therapy, new way to treat pain

Scrambler therapy to treat pain

By scrambling the information injured nerves send to the brain, this new form of therapy reduces the amount of pain sensation patients experience, particularly those suffering from chemotherapy induced peripheral neuropathy.   In this video, Salahadin Abdi, Ph.D., M.D., explains the science behind this technique.

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